Getting To Chalet Village Your Gatlinburg Vacation Home Away From Home Traffic in the Smokies can get heavy, especially along Highway 66 during peak travel seasons. (July and October are the highest travel months.) Take one of these less traveled and scenic routes to Gatlinburg and you're well on your way to the perfect mountain getaway. From Virginia: Take I-81 South to I-40 East to exit 435 (Newport) and follow Highway 321 South all the way into Gatlinburg. Approximate drive time from interstate: 45 min. From Lexington: From Knoxville take I-75 South to I640 East to I-40 East to exit 435 and follow Highway 321 South. Approximate drive time from interstate: 45 Min. From Chattanooga: Take Exit 81 on I-75 North and follow Highway 321 North to Gatlinburg through Maryville and Townsend. Approximate drive time from interstate: 1 hour and 10 minutes. From Nashville: Take I-75 South to exit 81 and follow Highway 321 North to Gatlinburg through Maryville and Townsend to Gatlinburg. Approximate drive time from interstate: 1 hour and 10 minutes. From Ashville: Take I-40 West to Exit 440 and follow Highway 321 south to Gatlinburg. Approximate drive time from interstate: 45 Minutes. From Atlanta: Take I-85 North to I-985 North to Us 23. Take US 23 to Highway 23/441 to Highway 74/441 through Cherokee, NC, to Gatlinburg. Approximate drive time: 4 hours and 10 minutes.